| Millennium: | 1st millennium BC |
| Centuries: | 4th century BC – 3rd century BC – 2nd century BC |
| Decades: | 280s BC 270s BC 260s BC – 250s BC – 240s BC 230s BC 220s BC |
| Years: | 259 BC 258 BC 257 BC 256 BC 255 BC 254 BC 253 BC 252 BC 251 BC 250 BC |
| Categories: | Births – Deaths – Architecture Establishments – Disestablishments |